Acts Online
GT Shield

Pharmacy Act, 1974 (Act No. 53 of 1974)

Board Notices

A Pharmacist who provides Pharmacist-Initiated Management of Antiretroviral Therapy (PIMART) services in South Africa: Scope of Practice, Competency Standards and the Criteria for Accreditation of a Pharmacist Initiated Management of Antiretroviral Therapy (PIMART) Course

Part 2: Competency Standards for a Pharmacist who provides Pharmacist-Initiated Management of Antiretroviral Therapy (PIMART) Services

Domain 5: Implement processes to prevent and manage drug interactions, adverse drug reactions and drug resistance

 

INTRODUCTION

 

The competencies required in the domain to implement processes to prevent and manage drug interactions, adverse drug reactions and drug resistance are:

 

5.1 Understand the importance of drug interactions, e.g. drug/drug and drug/disease;
5.2 Demonstrate in-depth knowledge of various ART drug interactions and reactions;
5.3 Prevent adverse drug interactions and reactions; and
5.4 Define the types and consequences of drug resistance.

 

DOMAIN 5: IMPLEMENT PROCESSES TO PREVENT AND MANAGE DRUG INTERACTIONS, ADVERSE DRUG REACTIONS AND DRUG RESISTANCE

COMPETENCIES

BEHAVIOURAL STATEMENTS
5.1 Understand the importance of drug interactions, e.g. drug/drug and drug/disease
5.1.1 Understanding the basics of drug interactions.
5.1.2 Listing and describing the consequences of drug interactions.

Range: therapeutic failure, drug resistance, life-threatening toxicities, poor adherence, increased costs.

5.1.3 Demonstrating knowledge and understanding of how the body processes drugs and of specified pharmacological concepts.

Range: pharmacokinetics and pharmacodynamics, therapeutic index, substrate, inhibitor, inducer.
5.2 Demonstrate in-depth knowledge of various ART drug interactions and reactions
5.2.1 Listing the ARVs most involved in drug interactions.
5.2.2 Describing medicines that may interact with ART and understand their mode of interaction and the management of interaction.
5.3 Prevent adverse drug interactions and reactions
5.3.1 Knowing how to prevent drug interactions.

Range: Comprehensive patient questioning and accessing useful resources.
5.4 Define the types and consequences of drug resistance
5.4.1 Demonstrating an understanding of the consequences of drug resistance.
5.4.2 Demonstrating an understanding of the mechanism of HIV drug resistance.
5.4.3 Defining acquired drug resistance, transmitted drug resistance, and pre-treatment drug resistance in patients.